› 4jnv

X-ray diffraction
1.85Å resolution

Crystal structure of the human Nup57CCS3* coiled-coil segment, space group C2

Released:
DOI: 10.2210/pdb4jnv/pdb
PDB entry 4jnv coloured by chain, front view.
PDB entry 4jnv coloured by chain, side view.
PDB entry 4jnv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Architecture of the fungal nuclear pore inner ring complex.
Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, Mayo DJ, Perriches T, Rundlet EJ, Jeon YE, Collins LN, Huber FM, Lin DH, Paduch M, Koide A, Lu V, Fischer J, Hurt E, Koide S, Kossiakoff AA, Hoelz A
Science 350 56-64 (2015)
PMID: 26316600

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin p54 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 40 amino acids
Theoretical weight: 4.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7Z3B4 (Residues: 453-491; Coverage: 8%)
Gene name: NUP54
Sequence domains: Nup54 C-terminal interacting domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: C2
Unit cell:
a: 70.506Å b: 36.623Å c: 63.179Å
α: 90° β: 104.39° γ: 90°
R-values:
R R work R free
0.241 0.237 0.277
Expression system: Escherichia coli

Quick links

Citations

21 review citations

The Nuclear Pore Complex as a Flexible and Dynamic Gate.
Knockenhauer et al. (2016)
20 more

1 mention without citation

Architecture of the fungal nuclear pore inner ring complex.
Stuwe et al. (2015)