› 4jue

X-ray diffraction
1.85Å resolution

Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9

Released:
DOI: 10.2210/pdb4jue/pdb
PDB entry 4jue coloured by chain, front view.
PDB entry 4jue coloured by chain, side view.
PDB entry 4jue coloured by chain, top view.
Source organism: Plasmodium falciparum 3D7
Primary publication:
Identification of biochemically distinct properties of the small ubiquitin-related modifier (SUMO) conjugation pathway in Plasmodium falciparum.
Reiter K, Mukhopadhyay D, Zhang H, Boucher LE, Kumar N, Bosch J, Matunis MJ
J Biol Chem 288 27724-36 (2013)
PMID: 23943616

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184651 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UBC core domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 161 amino acids
Theoretical weight: 18.36 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8I301 (Residues: 1-159; Coverage: 100%)
Gene name: PF3D7_0915100
Sequence domains: Ubiquitin-conjugating enzyme
Structure domains: Ubiquitin Conjugating Enzyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P21
Unit cell:
a: 28.87Å b: 94.39Å c: 124.89Å
α: 90° β: 90.02° γ: 90°
R-values:
R R work R free
0.149 0.146 0.188
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Post-translational modifications as key regulators of apicomplexan biology: insights from proteome-wide studies.
Yakubu et al. (2018)
4 more

3 mentions without citation

Identification of biochemically distinct properties of the small ubiquitin-related modifier (SUMO) conjugation pathway in Plasmodium falciparum.
Reiter et al. (2013)
2 more