› 4k2c

X-ray diffraction
3.23Å resolution

HSA Ligand Free

Released:
DOI: 10.2210/pdb4k2c/pdb
PDB entry 4k2c coloured by chain, front view.
PDB entry 4k2c coloured by chain, side view.
PDB entry 4k2c coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural mechanism of ring-opening reaction of glucose by human serum albumin.
Wang Y, Yu H, Shi X, Luo Z, Lin D, Huang M
J Biol Chem 288 15980-7 (2013)
PMID: 23592780

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136176 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chains: A, B
Molecule details ›
Chains: A, B
Length: 585 amino acids
Theoretical weight: 66.57 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P02768 (Residues: 25-609; Coverage: 99%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Sequence domains: Serum albumin family
Structure domains: Serum Albumin; Chain A, Domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 58.41Å b: 179.888Å c: 57.459Å
α: 90° β: 105.86° γ: 90°
R-values:
R R work R free
0.216 0.213 0.265
Expression system: Komagataella pastoris

Quick links

Citations

6 review citations

Interactive association of drugs binding to human serum albumin.
Yang et al. (2014)
5 more

22 mentions without citation

Structural mechanism of ring-opening reaction of glucose by human serum albumin.
Wang et al. (2013)
21 more