› 4kgb

X-ray diffraction
2.64Å resolution

Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster

Released:
DOI: 10.2210/pdb4kgb/pdb
PDB entry 4kgb coloured by chain, front view.
PDB entry 4kgb coloured by chain, side view.
PDB entry 4kgb coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structure of succinyl-CoA:3-ketoacid CoA transferase from Drosophila melanogaster.
Zhang M, Xu HY, Wang YC, Shi ZB, Zhang NN
Acta Crystallogr Sect F Struct Biol Cryst Commun 69 1089-93 (2013)
PMID: 24100554

Function and Biology Details

Reaction catalysed: 
Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194328 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Succinyl-CoA:3-ketoacid-coenzyme A transferase, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 487 amino acids
Theoretical weight: 51.72 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9W058 (Residues: 34-516; Coverage: 94%)
Gene names: CG1140, SCOT
Sequence domains: Coenzyme A transferase
Structure domains: Glutaconate Coenzyme A-transferase

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 76.638Å b: 101.921Å c: 122.457Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.204 0.261
Expression system: Escherichia coli

Quick links

Citations

2 citation in other articles

Redefining the coenzyme A transferase superfamily with a large set of manually annotated proteins.
Hackmann TJ. (2022)
1 more

1 mention without citation

Structure of succinyl-CoA:3-ketoacid CoA transferase from Drosophila melanogaster.
Zhang et al. (2013)