Function and Biology Details
Reaction catalysed:
A protein-L-glutamine + a protein-L-lysine = a protein with an N(6)-(gamma-glutamyl)-L-lysine cross-link + NH(3)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Coagulation factor XIII A chain and peptide (preferred)
PDBe Complex ID:
PDB-CPX-132549 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Coagulation factor XIII A chain
Molecule details ›
Chains: A, B
Length: 738 amino acids
Theoretical weight: 84.21 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 738 amino acids
Theoretical weight: 84.21 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P00488 (Residues: 2-732; Coverage: 100%)
Sequence domains:
- Transglutaminase family
- Transglutaminase-like superfamily
- Transglutaminase family, C-terminal ig like domain
