› 4l0r

X-ray diffraction
2.49Å resolution

Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.

Released:
DOI: 10.2210/pdb4l0r/pdb
PDB entry 4l0r coloured by chain, front view.
PDB entry 4l0r coloured by chain, side view.
PDB entry 4l0r coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Seetharaman J, Lew S, Su M, Ciccosanti C, Sahdev S, Acton TB, Xiao R, Everett JK, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183257 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Centrosomal protein of 57 kDa Chains: A, B
Molecule details ›
Chains: A, B
Length: 111 amino acids
Theoretical weight: 12.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86XR8 (Residues: 334-433; Coverage: 20%)
Gene names: CEP57, KIAA0092, TSP57
Sequence domains: Centrosome microtubule-binding domain of Cep57
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2
Unit cell:
a: 117.121Å b: 70.097Å c: 31.331Å
α: 90° β: 94.81° γ: 90°
R-values:
R R work R free
0.224 0.222 0.267
Expression system: Escherichia coli

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