› 4ll9

X-ray diffraction
2.69Å resolution

Crystal structure of D3D4 domain of the LILRB1 molecule

Released:
DOI: 10.2210/pdb4ll9/pdb
PDB entry 4ll9 coloured by chain, front view.
PDB entry 4ll9 coloured by chain, side view.
PDB entry 4ll9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding.
Nam G, Shi Y, Ryu M, Wang Q, Song H, Liu J, Yan J, Qi J, Gao GF
Protein Cell 4 761-70 (2013)
PMID: 23955630

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185548 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukocyte immunoglobulin-like receptor subfamily B member 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 196 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NHL6 (Residues: 222-417; Coverage: 31%)
Gene names: ILT2, LILRB1, LIR1, MIR7
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand IOD 12 x IOD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 121.257Å b: 71.976Å c: 75.036Å
α: 90° β: 95.2° γ: 90°
R-values:
R R work R free
0.246 0.245 0.275
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The Expanding Spectrum of Ligands for Leukocyte Ig-like Receptors.
Burshtyn et al. (2016)
3 more

3 mentions without citation

Structural basis for RIFIN-mediated activation of LILRB1 in malaria.
Harrison et al. (2020)
2 more