› 4lla

X-ray diffraction
2.5Å resolution

Crystal structure of D3D4 domain of the LILRB2 molecule

Released:
DOI: 10.2210/pdb4lla/pdb
PDB entry 4lla coloured by chain, front view.
PDB entry 4lla coloured by chain, side view.
PDB entry 4lla coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding.
Nam G, Shi Y, Ryu M, Wang Q, Song H, Liu J, Yan J, Qi J, Gao GF
Protein Cell 4 761-70 (2013)
PMID: 23955630

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185380 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukocyte immunoglobulin-like receptor subfamily B member 2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 198 amino acids
Theoretical weight: 21.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8N423 (Residues: 222-419; Coverage: 34%)
Gene names: ILT4, LILRB2, LIR2, MIR10
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 57.367Å b: 66.17Å c: 83.719Å
α: 90° β: 95.11° γ: 90°
R-values:
R R work R free
0.224 0.221 0.272
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The Expanding Spectrum of Ligands for Leukocyte Ig-like Receptors.
Burshtyn et al. (2016)
3 more

4 mentions without citation

A motif in LILRB2 critical for Angptl2 binding and activation.
Deng et al. (2014)
3 more