› 4m8v

X-ray diffraction
1.95Å resolution

Crystal structure of Human double mutant beta2-microglobulin Q8H-L65T

Released:
DOI: 10.2210/pdb4m8v/pdb
PDB entry 4m8v coloured by chain, front view.
PDB entry 4m8v coloured by chain, side view.
PDB entry 4m8v coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lai MH, Wu PH, Li CH, Chang CC, Chen CJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158314 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-2-microglobulin Chains: A, B
Molecule details ›
Chains: A, B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL15A1
Spacegroup: C2221
Unit cell:
a: 45.827Å b: 111.926Å c: 85.656Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.24
Expression system: Escherichia coli BL21(DE3)

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