› 4mew

X-ray diffraction
1.99Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195283 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein phosphatase 2A regulatory subunit B" subunit beta Chain: A
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 41.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y5P8 (Residues: 130-483; Coverage: 62%)
Gene names: PPP2R3B, PPP2R3L
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand GOL 2 x GOL
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 37.11Å b: 74.46Å c: 62.33Å
α: 90° β: 92.63° γ: 90°
R-values:
R R work R free
0.164 0.162 0.193
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

PP2A as a master regulator of the cell cycle.
Wlodarchak et al. (2016)
1 more

2 mentions without citation

Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A.
Dovega et al. (2014)
1 more