› 4mfv

X-ray diffraction
2.92Å resolution

Crystal structure of human CTNNBL1(residues 33~563)

Released:
DOI: 10.2210/pdb4mfv/pdb
PDB entry 4mfv coloured by chain, front view.
PDB entry 4mfv coloured by chain, side view.
PDB entry 4mfv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into the novel ARM-repeat protein CTNNBL1 and its association with the hPrp19-CDC5L complex.
Ahn JW, Kim S, Kim EJ, Kim YJ, Kim KJ
Acta Crystallogr D Biol Crystallogr 70 780-8 (2014)
PMID: 24598747

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186797 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-catenin-like protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 534 amino acids
Theoretical weight: 61.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WYA6 (Residues: 33-563; Coverage: 94%)
Gene names: C20orf33, CTNNBL1, PP8304
Sequence domains: Catenin-beta-like, Arm-motif containing nuclear
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P31
Unit cell:
a: 90.037Å b: 90.037Å c: 175.746Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.233 0.305
Expression system: Escherichia coli

Quick links

Citations

2 citation in other articles

Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID.
Kuhny et al. (2020)
1 more