› 4mhv

X-ray diffraction
2.45Å resolution

Crystal structure of the PNT domain of human ETS2

Released:
DOI: 10.2210/pdb4mhv/pdb
PDB entry 4mhv coloured by chain, front view.
PDB entry 4mhv coloured by chain, side view.
PDB entry 4mhv coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Newman JA, Cooper CDO, Krojer T, Shrestha L, Burgess-brown N, Arrowsmith CH, Bountra C, Edwards A, Gileadi O

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein C-ets-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 97 amino acids
Theoretical weight: 11.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15036 (Residues: 76-170; Coverage: 20%)
Gene name: ETS2
Sequence domains: Sterile alpha motif (SAM)/Pointed domain
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

3 bound ligands:
Ligand CA 1 x CA
Ligand GOL 3 x GOL
Ligand ACT 2 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P6122
Unit cell:
a: 64.44Å b: 64.44Å c: 263.71Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.23 0.236
Expression system: Escherichia coli

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