Function and Biology Details
Reaction catalysed:
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152584 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Molecule details ›
Chains: A, C
Length: 13 amino acids
Theoretical weight: 1.43 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 13 amino acids
Theoretical weight: 1.43 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical:
P33316 (Residues: 97-109; Coverage: 5%)
Importin subunit alpha-1
Molecule details ›
Chain: E
Length: 509 amino acids
Theoretical weight: 55.12 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 509 amino acids
Theoretical weight: 55.12 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P52293 (Residues: 70-528; Coverage: 87%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup:
P212121
Expression systems:
- Not provided
- Escherichia coli BL21(DE3)
