› 4n6v

X-ray diffraction
1.8Å resolution

Partial rotational order disorder structure of human stefin B

Released:
DOI: 10.2210/pdb4n6v/pdb
PDB entry 4n6v coloured by chain, front view.
PDB entry 4n6v coloured by chain, side view.
PDB entry 4n6v coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Partial rotational lattice order-disorder in stefin B crystals.
Renko M, Taler-Verčič A, Mihelič M, Zerovnik E, Turk D
Acta Crystallogr D Biol Crystallogr 70 1015-25 (2014)
PMID: 24699646

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137393 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cystatin-B Chains: 0, 1, 2, 3, 4, 5, 6, 7, 8, 9
Molecule details ›
Chains: 0, 1, 2, 3, 4, 5, 6, 7, 8, 9
Length: 91 amino acids
Theoretical weight: 10.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04080 (Residues: 8-98; Coverage: 93%)
Gene names: CST6, CSTB, STFB
Sequence domains: Cystatin domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: I4
Unit cell:
a: 95.559Å b: 95.559Å c: 254.977Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.19 0.234
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Putative alternative functions of human stefin B (cystatin B): binding to amyloid-beta, membranes, and copper.
Žerovnik E. (2017)
2 other articles

7 mentions without citation

Understanding protein domain-swapping using structure-based models of protein folding.
Mascarenhas et al. (2017)
6 more