› 4nc6

X-ray diffraction
1.8Å resolution

Tbc domain of human rab gtpase-activating protein 1

Released:
DOI: 10.2210/pdb4nc6/pdb
PDB entry 4nc6 coloured by chain, front view.
PDB entry 4nc6 coloured by chain, side view.
PDB entry 4nc6 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Janowski R, Boutin M, Coll M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195212 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rab GTPase-activating protein 1 Chain: A
Molecule details ›
Chain: A
Length: 314 amino acids
Theoretical weight: 37.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y3P9 (Residues: 536-849; Coverage: 29%)
Gene names: HSPC094, RABGAP1
Sequence domains: Rab-GTPase-TBC domain
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ACT 1 x ACT
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P212121
Unit cell:
a: 43.15Å b: 51.39Å c: 132.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.16 0.215
Expression system: Escherichia coli BL21(DE3)

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