› 4nhu

X-ray diffraction
2.9Å resolution

The M33 TCR p3M33l/H-2 Ld Complex

Released:
DOI: 10.2210/pdb4nhu/pdb
PDB entry 4nhu coloured by chain, front view.
PDB entry 4nhu coloured by chain, side view.
PDB entry 4nhu coloured by chain, top view.
Source organisms:
Entry authors: Birnbaum ME, Adams JJ, Garcia KC

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-105326 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
T cell receptor alpha chain constant; T-cell receptor alpha chain V region PHDS58 Chains: A, C
Molecule details ›
Chains: A, C
Length: 219 amino acids
Theoretical weight: 24.28 KDa
Source organisms: Expression system: Trichoplusia ni
UniProt:
  • Canonical: P01738 (Residues: 20-130; Coverage: 100%)
  • Canonical: P01848 (Residues: 1-93; Coverage: 66%)
Gene names: TCRA, TRAC
Sequence domains:
Structure domains: Immunoglobulins
T cell receptor beta constant 2; T-cell receptor beta chain V region C5 Chains: B, D
Molecule details ›
Chains: B, D
Length: 254 amino acids
Theoretical weight: 28.05 KDa
Source organisms: Expression system: Trichoplusia ni
UniProt:
  • Canonical: P04213 (Residues: 9-122; Coverage: 96%)
  • Canonical: A0A5B9 (Residues: 1-129; Coverage: 73%)
Gene names: TCRBC2, TRBC2
Sequence domains:
Structure domains: Immunoglobulins
H-2 class I histocompatibility antigen, L-D alpha chain Chains: E, G
Molecule details ›
Chains: E, G
Length: 204 amino acids
Theoretical weight: 23.11 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01897 (Residues: 25-204; Coverage: 53%)
Gene name: H2-L
Sequence domains: Class I Histocompatibility antigen, domains alpha 1 and 2
Structure domains: MHC class I-like antigen recognition-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P1
Unit cell:
a: 49.76Å b: 92.8Å c: 94.95Å
α: 112.29° β: 103.57° γ: 102.37°
R-values:
R R work R free
0.231 0.229 0.26
Expression systems:
  • Trichoplusia ni
  • Escherichia coli

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