› 4nkn

X-ray diffraction
2.79Å resolution

The Crystal Structure of the N-terminal domain of COMMD9

Released:
DOI: 10.2210/pdb4nkn/pdb
PDB entry 4nkn coloured by chain, front view.
PDB entry 4nkn coloured by chain, side view.
PDB entry 4nkn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into the architecture and membrane interactions of the conserved COMMD proteins.
Healy MD, Hospenthal MK, Hall RJ, Chandra M, Chilton M, Tillu V, Chen KE, Celligoi DJ, McDonald FJ, Cullen PJ, Lott JS, Collins BM, Ghai R
Elife 7 (2018)
PMID: 30067224

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192793 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
COMM domain-containing protein 9 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 121 amino acids
Theoretical weight: 13.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9P000 (Residues: 2-117; Coverage: 59%)
Gene names: COMMD9, HSPC166
Sequence domains: COMMD9, N-terminal domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Unit cell:
a: 89.69Å b: 79.757Å c: 131.164Å
α: 90° β: 90.61° γ: 90°
R-values:
R R work R free
0.212 0.21 0.25
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

COMMD proteins function and their regulating roles in tumors.
You et al. (2023)
2 more