› 4o6x

X-ray diffraction
2.1Å resolution

Crystal structure of human Ankyrin G death domain

Released:
DOI: 10.2210/pdb4o6x/pdb
PDB entry 4o6x coloured by chain, front view.
PDB entry 4o6x coloured by chain, side view.
PDB entry 4o6x coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human Ankyrin G death domain.
Liu Y, Zhang Y, Wang JH
Proteins 82 3476-82 (2014)
PMID: 25307106

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-171452 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ankyrin-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 121 amino acids
Theoretical weight: 13.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q12955 (Residues: 4088-4199; Coverage: 3%)
Gene name: ANK3
Sequence domains: Death domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 44.452Å b: 56.817Å c: 81.949Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.182 0.231
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

Association analysis of ANK3 variants with bipolar disorder in the Korean population.
Cho et al. (2017)

3 mentions without citation

Assembly of platforms for signal transduction in the new era: dimerization, helical filament assembly, and beyond.
Ha et al. (2020)
2 more