› 4o9i

X-ray diffraction
2.6Å resolution

Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding

Released:
DOI: 10.2210/pdb4o9i/pdb
PDB entry 4o9i coloured by chain, front view.
PDB entry 4o9i coloured by chain, side view.
PDB entry 4o9i coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wiggs KR, Chruszcz M, Su X, Minor W, Khorasanizadeh S

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172109 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromodomain-helicase-DNA-binding protein 4 Chain: X
Molecule details ›
Chain: X
Length: 202 amino acids
Theoretical weight: 25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14839 (Residues: 499-677; Coverage: 9%)
Gene name: CHD4
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 50.211Å b: 60.475Å c: 92.988Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.211 0.264
Expression system: Escherichia coli

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