› 4oe9

X-ray diffraction
1.55Å resolution

The crystal structure of the n-terminal domain of COMMD9

Released:
DOI: 10.2210/pdb4oe9/pdb
PDB entry 4oe9 coloured by chain, front view.
PDB entry 4oe9 coloured by chain, side view.
PDB entry 4oe9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into the architecture and membrane interactions of the conserved COMMD proteins.
Healy MD, Hospenthal MK, Hall RJ, Chandra M, Chilton M, Tillu V, Chen KE, Celligoi DJ, McDonald FJ, Cullen PJ, Lott JS, Collins BM, Ghai R
Elife 7 (2018)
PMID: 30067224

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192792 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
COMM domain-containing protein 9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 121 amino acids
Theoretical weight: 13.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9P000 (Residues: 1-117; Coverage: 59%)
Gene names: COMMD9, HSPC166
Sequence domains: COMMD9, N-terminal domain

Ligands and Environments

2 bound ligands:
Ligand CIT 3 x CIT
Ligand K 1 x K
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P1
Unit cell:
a: 28.49Å b: 35.58Å c: 54.3Å
α: 104.03° β: 93.3° γ: 91.11°
R-values:
R R work R free
0.136 0.134 0.165
Expression system: Escherichia coli

Quick links

Citations

3 review citations

COMMD proteins function and their regulating roles in tumors.
You et al. (2023)
2 more

3 mentions without citation

Systems-wide Studies Uncover Commander, a Multiprotein Complex Essential to Human Development.
Mallam et al. (2017)
2 more