› 4of0

X-ray diffraction
2.3Å resolution

Crystal Structure of SYG-1 D1-D2, refolded

Released:
DOI: 10.2210/pdb4of0/pdb
PDB entry 4of0 coloured by chain, front view.
PDB entry 4of0 coloured by chain, side view.
PDB entry 4of0 coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Extracellular architecture of the SYG-1/SYG-2 adhesion complex instructs synaptogenesis.
Özkan E, Chia PH, Wang RR, Goriatcheva N, Borek D, Otwinowski Z, Walz T, Shen K, Garcia KC
Cell 156 482-94 (2014)
PMID: 24485456

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109405 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptogenesis protein syg-1 Chain: A
Molecule details ›
Chain: A
Length: 257 amino acids
Theoretical weight: 28.58 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: B1Q236 (Residues: 19-271; Coverage: 36%)
Gene names: K02E10.8, syg-1
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2
Unit cell:
a: 86.545Å b: 32.065Å c: 102.235Å
α: 90° β: 113.84° γ: 90°
R-values:
R R work R free
0.205 0.201 0.245
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Mechanisms of myoblast fusion during muscle development.
Kim et al. (2015)
14 more