› 4of6

X-ray diffraction
1.7Å resolution

Crystal Structure of SYG-1 D1, Crystal form 1

Released:
DOI: 10.2210/pdb4of6/pdb
PDB entry 4of6 coloured by chain, front view.
PDB entry 4of6 coloured by chain, side view.
PDB entry 4of6 coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Extracellular architecture of the SYG-1/SYG-2 adhesion complex instructs synaptogenesis.
Özkan E, Chia PH, Wang RR, Goriatcheva N, Borek D, Otwinowski Z, Walz T, Shen K, Garcia KC
Cell 156 482-94 (2014)
PMID: 24485456

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109405 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Synaptogenesis protein syg-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 120 amino acids
Theoretical weight: 13.37 KDa
Source organism: Caenorhabditis elegans
Expression system: Trichoplusia ni
UniProt:
  • Canonical: B1Q236 (Residues: 19-129; Coverage: 16%)
Gene names: K02E10.8, syg-1
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
1 bound ligand:
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P42212
Unit cell:
a: 84.809Å b: 84.809Å c: 74.129Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.175 0.206
Expression system: Trichoplusia ni

Quick links

Citations

16 review citations

Mechanisms of myoblast fusion during muscle development.
Kim et al. (2015)
15 more

1 mention without citation

Drosophila OTK Is a Glycosaminoglycan-Binding Protein with High Conformational Flexibility.
Rozbesky et al. (2020)