› 4oj2

X-ray diffraction
3.05Å resolution

The structure of aquaporin

Released:
DOI: 10.2210/pdb4oj2/pdb
PDB entry 4oj2 coloured by chain, front view.
PDB entry 4oj2 coloured by chain, side view.
PDB entry 4oj2 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vahedi-Faridi A, Lodowski D, Engel A, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aquaporin-2 Chain: X
Molecule details ›
Chain: X
Length: 274 amino acids
Theoretical weight: 29.17 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P41181 (Residues: 1-271; Coverage: 100%)
Gene name: AQP2
Sequence domains: Major intrinsic protein
Structure domains: Glycerol uptake facilitator protein.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P4212
Unit cell:
a: 95.717Å b: 95.717Å c: 79.058Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.259 0.257 0.299
Expression system: Spodoptera frugiperda

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