› 4oo5

X-ray diffraction
1.54Å resolution

Crystal Structure of S-nitrosated Human Thioredoxin Mutant

Released:
DOI: 10.2210/pdb4oo5/pdb
PDB entry 4oo5 coloured by chain, front view.
PDB entry 4oo5 coloured by chain, side view.
PDB entry 4oo5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: The J, Weichsel A, Montfort WR

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145348 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10599 (Residues: 1-105; Coverage: 100%)
Gene names: TRDX, TRX, TRX1, TXN
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
1 modified residue:
Ligand SNC 1 x SNC

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: C2
Unit cell:
a: 67.008Å b: 26.038Å c: 51.09Å
α: 90° β: 94.83° γ: 90°
R-values:
R R work R free
0.194 0.191 0.248
Expression system: Escherichia coli BL21(DE3)

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