4oqt

X-ray diffraction
3.23Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero hexamer
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-180169 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 Chain: A
Molecule details ›
Chain: A
Length: 478 amino acids
Theoretical weight: 54.44 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q96FE5 (Residues: 40-517; Coverage: 82%)
Gene names: LERN1, LINGO1, LRRN6A, UNQ201/PRO227
Sequence domains:
Structure domains:
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.65 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q6PIL8 (Residues: 24-236; Coverage: 98%)
Gene name: IGK@
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chain: H
Molecule details ›
Chain: H
Length: 235 amino acids
Theoretical weight: 24.75 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: S6B291 (Residues: 20-117, 118-253; Coverage: 52%)
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P6522
Unit cell:
a: 207.47Å b: 207.47Å c: 140.865Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.192 0.256
Expression system: Cricetulus griseus