› 4ouh

X-ray diffraction
2Å resolution

Crystal structure of the FP domain of Human PI31 Proteasome Inhibitor

Released:
DOI: 10.2210/pdb4ouh/pdb
PDB entry 4ouh coloured by chain, front view.
PDB entry 4ouh coloured by chain, side view.
PDB entry 4ouh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The FP domains of PI31 and Fbxo7 have the same protein fold but very different modes of protein-protein interaction.
Shang J, Huang X, Du Z
J Biomol Struct Dyn 33 1528-38 (2015)
PMID: 25266262

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187676 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasome inhibitor PI31 subunit Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 163 amino acids
Theoretical weight: 18.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92530 (Residues: 1-158; Coverage: 58%)
Gene name: PSMF1
Sequence domains: PI31 proteasome regulator N-terminal
Structure domains: Protein Transport Mog1p; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P212121
Unit cell:
a: 58.83Å b: 97.67Å c: 108.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.186 0.238
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic Remodeling.
Rathje et al. (2019)
2 more