Function and Biology Details
Reaction catalysed:
(1a) [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [RBR-type E3 ubiquitin transferase]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [RBR-type E3 ubiquitin transferase]-S-ubiquitinyl-L-cysteine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131553 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
NF-kappa-B essential modulator
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 10.65 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
Structure domains: Nemo cc2-lz domain - 1d5 darpin complex
Length: 90 amino acids
Theoretical weight: 10.65 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
O88522 (Residues: 250-339; Coverage: 22%)
Sequence domains: Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
Structure domains: Nemo cc2-lz domain - 1d5 darpin complex
E3 ubiquitin-protein ligase RNF31
Molecule details ›
Chain: G
Length: 30 amino acids
Theoretical weight: 3.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Length: 30 amino acids
Theoretical weight: 3.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: Q96EP0 (Residues: 350-379; Coverage: 3%)
