Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117958 (preferred)
Entry contents:
2 distinct polypeptide molecules
3 distinct DNA molecules
3 distinct DNA molecules
Macromolecules (5 distinct):
Crossover junction endonuclease MUS81
Molecule details ›
Chains: A, C, E, G
Length: 306 amino acids
Theoretical weight: 34.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 306 amino acids
Theoretical weight: 34.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q96NY9 (Residues: 246-551; Coverage: 56%)
Sequence domains:
Crossover junction endonuclease EME1
Molecule details ›
Chains: B, D, F, H
Length: 393 amino acids
Theoretical weight: 43.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 393 amino acids
Theoretical weight: 43.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q96AY2 (Residues: 178-570; Coverage: 69%)
Sequence domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PAL/PLS BEAMLINE 5C (4A)
Spacegroup:
C2221
Expression system: Escherichia coli
