› 4pd3

X-ray diffraction
2.84Å resolution

Crystal Structure of Rigor-Like Human Nonmuscle Myosin-2B

Released:
DOI: 10.2210/pdb4pd3/pdb
PDB entry 4pd3 coloured by chain, front view.
PDB entry 4pd3 coloured by chain, side view.
PDB entry 4pd3 coloured by chain, top view.
Source organisms:
Primary publication:
Crystal structure of the rigor-like human non-muscle myosin-2 motor domain.
Münnich S, Pathan-Chhatbar S, Manstein DJ
FEBS Lett 588 4754-60 (2014)
PMID: 25451231

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138424 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-actinin A; Myosin-10 Chains: A, B
Molecule details ›
Chains: A, B
Length: 1032 amino acids
Theoretical weight: 118.72 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P35580 (Residues: 1-782; Coverage: 40%)
  • Canonical: P05095 (Residues: 265-502; Coverage: 28%)
Gene names: DDB_G0268632, MYH10, abpA, actnA
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: P21
Unit cell:
a: 65.85Å b: 157.87Å c: 143.48Å
α: 90° β: 94.21° γ: 90°
R-values:
R R work R free
0.254 0.253 0.288
Expression system: Spodoptera frugiperda

Quick links

Citations

1 review citation

Towards a structural understanding of the remodeling of the actin cytoskeleton.
Merino et al. (2020)
7 other articles

5 mentions without citation

Potential entry receptors for human γ-herpesvirus into epithelial cells: A plausible therapeutic target for viral infections.
Rani et al. (2021)
4 more