› 4pqd

X-ray diffraction
1.33Å resolution

The longer crystal structure of the grow factor like domain from Beta amypoid precusor protein (APP22-126)

Released:
DOI: 10.2210/pdb4pqd/pdb
PDB entry 4pqd coloured by chain, front view.
PDB entry 4pqd coloured by chain, side view.
PDB entry 4pqd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tan X, Li W, Wang Z

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138353 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-APP Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05067 (Residues: 22-126; Coverage: 14%)
Gene names: A4, AD1, APP
Sequence domains: Amyloid A4 N-terminal heparin-binding
Structure domains: Amyloidogenic glycoprotein, heparin-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 32.755Å b: 49.025Å c: 65.141Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.17 0.186
Expression system: Escherichia coli

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