› 4q1p

X-ray diffraction
1.46Å resolution

Galectin-1 in Complex with Ligand NB169

Released:
DOI: 10.2210/pdb4q1p/pdb
PDB entry 4q1p coloured by chain, front view.
PDB entry 4q1p coloured by chain, side view.
PDB entry 4q1p coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Grimm C, Bertleff-Zieschang N

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
monomeric
Assembly name:
PDBe Complex ID:
PDB-CPX-140624 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 136 amino acids
Theoretical weight: 15.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09382 (Residues: 1-135; Coverage: 100%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:
Ligand 2XT 2 x 2XT
Ligand BME 1 x BME
Ligand SO4 1 x SO4
1 modified residue:
Ligand CME 6 x CME

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 43.267Å b: 58.373Å c: 111.066Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.151 0.149 0.188
Expression system: Escherichia coli

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