› 4q2n

X-ray diffraction
2Å resolution

INADL PDZ3 in Complex with a Phage-Derived Peptide

Released:
DOI: 10.2210/pdb4q2n/pdb
PDB entry 4q2n coloured by chain, front view.
PDB entry 4q2n coloured by chain, side view.
PDB entry 4q2n coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A structural portrait of the PDZ domain family.
Ernst A, Appleton BA, Ivarsson Y, Zhang Y, Gfeller D, Wiesmann C, Sidhu SS
J Mol Biol 426 3509-19 (2014)
PMID: 25158098

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185570 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
InaD-like protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 103 amino acids
Theoretical weight: 11.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NI35 (Residues: 362-452; Coverage: 5%)
Gene names: CIPP, INADL, PATJ
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

1 bound ligand:
Ligand EDO 6 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P21
Unit cell:
a: 58.957Å b: 65.156Å c: 82.543Å
α: 90° β: 101.1° γ: 90°
R-values:
R R work R free
0.204 0.201 0.253
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Structural Features of Tight-Junction Proteins.
Heinemann et al. (2019)
9 more

1 mention without citation

MR-REX: molecular replacement by cooperative conformational search and occupancy optimization on low-accuracy protein models.
Virtanen et al. (2018)