Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA-directed DNA polymerase, family B
- DNA polymerase family B, thumb domain
- DNA-directed DNA polymerase, family B, conserved site
- DNA polymerase alpha catalytic subunit, catalytic domain
- DNA polymerase, palm domain superfamily
- DNA/RNA polymerase superfamily
- DNA-directed DNA polymerase, family B, multifunctional domain
- Ribonuclease H superfamily
2 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-118008 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
1 distinct RNA molecule
1 distinct DNA molecule
1 distinct RNA molecule
Macromolecules (3 distinct):
DNA polymerase alpha catalytic subunit
Molecule details ›
Chains: A, E
Length: 922 amino acids
Theoretical weight: 105.58 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 922 amino acids
Theoretical weight: 105.58 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P09884 (Residues: 336-1257; Coverage: 63%)
Sequence domains:
Structure domains:
