Function and Biology Details
Reaction catalysed:
(1a) NAD(+) = cyclic ADP-ribose + nicotinamide
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Interleukin-18 and Interleukin-18 receptor 1 (preferred)
PDBe Complex ID:
PDB-CPX-171711 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-18 receptor 1
Molecule details ›
Chains: A, C
Length: 317 amino acids
Theoretical weight: 36.65 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Structure domains: Immunoglobulins
Length: 317 amino acids
Theoretical weight: 36.65 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q13478 (Residues: 19-329; Coverage: 60%)
Structure domains: Immunoglobulins
Interleukin-18
Molecule details ›
Chains: B, D
Length: 157 amino acids
Theoretical weight: 18.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Length: 157 amino acids
Theoretical weight: 18.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q14116 (Residues: 37-193; Coverage: 81%)
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
