Function and Biology Details
Reaction catalysed:
Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assemblies composition:
Assembly name:
Fanconi-associated nuclease 1 (preferred)
PDBe Complex ID:
PDB-CPX-195145 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fanconi-associated nuclease 1
Molecule details ›
Chains: A, B
Length: 640 amino acids
Theoretical weight: 72.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 640 amino acids
Theoretical weight: 72.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9Y2M0 (Residues: 370-1009; Coverage: 63%)
Sequence domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-C
Spacegroup:
C2221
Expression system: Escherichia coli BL21(DE3)
