Function and Biology Details
Reaction catalysed:
3 ATP = pppA2'p5'A2'p5'A + 2 diphosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
2'-5'-oligoadenylate synthase 3 and RNA (preferred)
PDBe Complex ID:
PDB-CPX-195369 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
2 distinct RNA molecules
Macromolecules (3 distinct):
2'-5'-oligoadenylate synthase 3
Molecule details ›
Chain: A
Length: 373 amino acids
Theoretical weight: 41.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
Structure domains:
Length: 373 amino acids
Theoretical weight: 41.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9Y6K5 (Residues: 1-371; Coverage: 34%)
Sequence domains: 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X29A
Spacegroup:
P21
Expression systems:
- Escherichia coli
- Not provided
