› 4tgf

Solution NMR

SOLUTION STRUCTURES OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA DERIVED FROM 1*H NMR DATA

Released:
DOI: 10.2210/pdb4tgf/pdb
PDB entry 4tgf coloured by chain, ensemble of 4 models, front view.
PDB entry 4tgf coloured by chain, ensemble of 4 models, side view.
PDB entry 4tgf coloured by chain, ensemble of 4 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structures of human transforming growth factor alpha derived from 1H NMR data.
Kline TP, Brown FK, Brown SC, Jeffs PW, Kopple KD, Mueller L
Biochemistry 29 7805-13 (1990)
PMID: 2261437

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134053 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transforming growth factor alpha Chain: A
Molecule details ›
Chain: A
Length: 50 amino acids
Theoretical weight: 5.56 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01135 (Residues: 40-89; Coverage: 37%)
Gene name: TGFA
Structure domains: Laminin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

2 review citations

Structure-function relationships for the EGF/TGF-alpha family of mitogens.
Groenen et al. (1994)
1 more

1 mention without citation

Chemical shift prediction for protein structure calculation and quality assessment using an optimally parameterized force field.
Nielsen et al. (2012)