4u0a

X-ray diffraction
2.05Å resolution

Hexameric HIV-1 CA in complex with CPSF6 peptide, P6 crystal form

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-146195 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Capsid protein p24 Chain: A
Molecule details ›
Chain: A
Length: 231 amino acids
Theoretical weight: 25.46 KDa
Source organism: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12493 (Residues: 133-363; Coverage: 46%)
Gene name: gag
Sequence domains:
Structure domains:
Cleavage and polyadenylation specificity factor subunit 6 Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.55 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q16630 (Residues: 276-290; Coverage: 3%)
Gene names: CFIM68, CPSF6

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P6
Unit cell:
a: 91.549Å b: 91.549Å c: 57.001Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.215 0.213 0.252
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided