4u0d

X-ray diffraction
3Å resolution

Hexameric HIV-1 CA in complex with Nup153 peptide, P212121 crystal form

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-146191 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Capsid protein p24 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 231 amino acids
Theoretical weight: 25.46 KDa
Source organism: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12493 (Residues: 133-363; Coverage: 46%)
Gene name: gag
Sequence domains:
Structure domains:
Nuclear pore complex protein Nup153 Chains: M, N, O, P, Q, R
Molecule details ›
Chains: M, N, O, P, Q, R
Length: 17 amino acids
Theoretical weight: 1.69 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49790 (Residues: 1407-1423; Coverage: 1%)
Gene name: NUP153

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P212121
Unit cell:
a: 135.38Å b: 138.06Å c: 211.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.247 0.246 0.267
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided