› 4udt

X-ray diffraction
1.35Å resolution

T cell receptor (TRAV22,TRBV7-9) structure

Released:
DOI: 10.2210/pdb4udt/pdb
PDB entry 4udt coloured by chain, front view.
PDB entry 4udt coloured by chain, side view.
PDB entry 4udt coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition.
Rödström KE, Regenthal P, Lindkvist-Petersson K
PLoS One 10 e0131988 (2015)
PMID: 26147596

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-100937 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T cell receptor alpha chain constant; T cell receptor alpha variable 22 Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 22.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0B4J277 (Residues: 21-110; Coverage: 100%)
  • Canonical: P01848 (Residues: 1-93; Coverage: 66%)
Gene names: TCRA, TRAC, TRAV22
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein; T cell receptor beta constant 2 Chain: B
Molecule details ›
Chain: B
Length: 243 amino acids
Theoretical weight: 27.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A5A3 (Residues: 20-115; Coverage: 99%)
  • Canonical: A0A5B9 (Residues: 1-129; Coverage: 73%)
Gene names: TCRBC2, TCRBV6S4A1, TRBC2
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 39.071Å b: 79.747Å c: 69.035Å
α: 90° β: 105.86° γ: 90°
R-values:
R R work R free
0.158 0.156 0.193
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Staphylococcal enterotoxins and enterotoxin-like toxins with special reference to dairy products: An overview.
Benkerroum N. (2018)
1 more

3 mentions without citation

Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition.
Rödström et al. (2015)
2 more