Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Bone morphogenetic protein 2 and Hemojuvelin (preferred)
PDBe Complex ID:
PDB-CPX-146278 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bone morphogenetic protein 2
Molecule details ›
Chains: A, B
Length: 114 amino acids
Theoretical weight: 12.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 114 amino acids
Theoretical weight: 12.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P12643 (Residues: 283-396; Coverage: 31%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Hemojuvelin
Molecule details ›
Chains: C, D
Length: 122 amino acids
Theoretical weight: 12.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Repulsive guidance molecule (RGM) N-terminus
Length: 122 amino acids
Theoretical weight: 12.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q6ZVN8 (Residues: 35-145; Coverage: 28%)
Sequence domains: Repulsive guidance molecule (RGM) N-terminus
