4uuc

X-ray diffraction
1.8Å resolution

Crystal structure of human ASB11 ankyrin repeat domain

Released:
Source organism: Homo sapiens
Entry authors: Pinkas DM, Sanvitale C, Kragh Nielsen T, Guo K, Sorrell F, Berridge G, Ayinampudi V, Wang D, Newman JA, Tallant C, Chaikuad A, Canning P, Kopec J, Krojer T, Vollmar M, Allerston CK, Chalk R, Burgess-Brown N, von Delft F, Arrowsmith CH, Edwards A, Bountra C, Bullock A

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-186783 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ankyrin repeat and SOCS box protein 11 Chain: A
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8WXH4 (Residues: 64-287; Coverage: 69%)
Gene name: ASB11
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 43.215Å b: 64.375Å c: 89.603Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 0.162 0.202
Expression system: Escherichia coli BL21