› 4wms

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142555 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Induced myeloid leukemia cell differentiation protein Mcl-1; Maltose/maltodextrin-binding periplasmic protein Chain: A
Molecule details ›
Chain: A
Length: 518 amino acids
Theoretical weight: 57.31 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
  • Canonical: Q07820 (Residues: 174-321; Coverage: 42%)
Gene names: BCL2L3, JW3994, MCL1, b4034, malE
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
Carbohydrate polymer
3 bound ligands:
Ligand MG 1 x MG
Ligand EDO 2 x EDO
Ligand FMT 10 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P21212
Unit cell:
a: 99.05Å b: 136.1Å c: 37.51Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.174 0.214
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Guidelines for the successful generation of protein-ligand complex crystals.
Müller I. (2017)
8 other articles

5 mentions without citation

Crystal structures of MBP fusion proteins.
Waugh DS. (2016)
4 more