Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139514 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Macrophage colony-stimulating factor 1 receptor
Molecule details ›
Chain: A
Length: 493 amino acids
Theoretical weight: 54.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 493 amino acids
Theoretical weight: 54.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P07333 (Residues: 20-504; Coverage: 51%)
Sequence domains:
Macrophage colony-stimulating factor 1 43 kDa subunit
Molecule details ›
Chain: B
Length: 170 amino acids
Theoretical weight: 19.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Macrophage colony stimulating factor-1 (CSF-1)
Length: 170 amino acids
Theoretical weight: 19.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P09603 (Residues: 33-181; Coverage: 29%)
Sequence domains: Macrophage colony stimulating factor-1 (CSF-1)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06SA
Spacegroup:
P6122
Expression systems:
- Homo sapiens
- Escherichia coli
