4wrq

X-ray diffraction
2.41Å resolution

Crystal Structure of 14-3-3 zeta with Chibby peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-158990 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein zeta/delta Chains: A, B
Molecule details ›
Chains: A, B
Length: 246 amino acids
Theoretical weight: 27.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P63104 (Residues: 1-245; Coverage: 100%)
Gene name: YWHAZ
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Protein chibby homolog 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 18 amino acids
Theoretical weight: 2.09 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9Y3M2 (Residues: 12-29; Coverage: 14%)
Gene names: ARB1, C22orf2, CBY, CBY1, HRIHFB2025, PGEA1

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P212121
Unit cell:
a: 70.83Å b: 71.96Å c: 130.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.203 0.256
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided