› 4wtz

X-ray diffraction
2.52Å resolution

Human CEACAM6-CEACAM8 N-domain heterodimer complex

Released:
DOI: 10.2210/pdb4wtz/pdb
PDB entry 4wtz coloured by chain, front view.
PDB entry 4wtz coloured by chain, side view.
PDB entry 4wtz coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kirouac KN, Prive GG

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152187 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Carcinoembryonic antigen-related cell adhesion molecule 6 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 108 amino acids
Theoretical weight: 11.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P40199 (Residues: 34-141; Coverage: 35%)
Gene names: CEACAM6, NCA
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
Carcinoembryonic antigen-related cell adhesion molecule 8 Chains: G, H, I, J, K, L
Molecule details ›
Chains: G, H, I, J, K, L
Length: 109 amino acids
Theoretical weight: 12.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P31997 (Residues: 34-141; Coverage: 34%)
Gene names: CEACAM8, CGM6
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand NI 3 x NI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 109.146Å b: 113.582Å c: 123.151Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.205 0.234
Expression system: Escherichia coli

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