› 4x1d

X-ray diffraction
2.8Å resolution

Ytterbium-bound human serum transferrin

Released:
DOI: 10.2210/pdb4x1d/pdb
PDB entry 4x1d coloured by chain, front view.
PDB entry 4x1d coloured by chain, side view.
PDB entry 4x1d coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
"Anion clamp" allows flexible protein to impose coordination geometry on metal ions.
Wang M, Lai TP, Wang L, Zhang H, Yang N, Sadler PJ, Sun H
Chem Commun (Camb) 51 7867-70 (2015)
PMID: 25854324

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136222 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serotransferrin Chains: A, B
Molecule details ›
Chains: A, B
Length: 679 amino acids
Theoretical weight: 75.28 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02787 (Residues: 20-698; Coverage: 100%)
Gene names: PRO1400, TF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

3 bound ligands:
Ligand YB 2 x YB
Ligand MLI 2 x MLI
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 156.502Å b: 136.863Å c: 107.843Å
α: 90° β: 90.41° γ: 90°
R-values:
R R work R free
0.2 0.198 0.231

Quick links

Citations

1 review citation

Computational approaches for deciphering the equilibrium and kinetic properties of iron transport proteins.
Abdizadeh et al. (2017)
13 other articles