Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Coagulation factor XIIa heavy chain (preferred)
PDBe Complex ID:
PDB-CPX-133243 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Coagulation factor XIIa light chain
Molecule details ›
Chain: A
Length: 255 amino acids
Theoretical weight: 27.63 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 255 amino acids
Theoretical weight: 27.63 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
P00748 (Residues: 373-615; Coverage: 41%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
