Function and Biology Details
Reaction catalysed:
(1a) S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [HECT-type E3 ubiquitin transferase]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + S-ubiquitinyl-[HECT-type E3 ubiquitin transferase]-L-cysteine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Maltose/Cyclodextrin ABC transporter, substrate-binding protein
- p53 tumour suppressor family
- E6 superfamily
- E6 early regulatory protein
- p53, DNA-binding domain
- p53-like transcription factor, DNA-binding domain superfamily
- p53/RUNT-type transcription factor, DNA-binding domain superfamily
- Solute-binding family 1, conserved site
1 more domain
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-136585 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):