› 4xuu

X-ray diffraction
2.62Å resolution

The hSac2 domain from human phosphoinositide phosphatase Sac2

Released:
DOI: 10.2210/pdb4xuu/pdb
PDB entry 4xuu coloured by chain, front view.
PDB entry 4xuu coloured by chain, side view.
PDB entry 4xuu coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Hsu F, Mao Y

Function and Biology Details

Reaction catalysed: 
Myo-inositol phosphate + H(2)O = myo-inositol + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195131 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositide phosphatase SAC2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 169 amino acids
Theoretical weight: 19.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y2H2 (Residues: 593-760; Coverage: 15%)
Gene names: INPP5F, KIAA0966, MSTP007, MSTP047, SAC2
Sequence domains: Inositol phosphatase

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 20 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 61.772Å b: 82.852Å c: 157.695Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.248 0.287
Expression system: Escherichia coli

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